The CRISPR-Cas9 gene editing system has revolutionized genetic engineering. Over the last decade, this technology has exploded at a breathtaking pace due to its simplicity, scalability, affordability and adaptability. Currently, the CRISPR-Cas9 system is employed in molecular biology laboratories all around the world and has been used to edit the genomes of a myriad of organisms from bacteria to yeasts to plants to mammals. This is particularly true in the cancer immunotherapy sphere, where the CRISPR-Cas9 system has been successfully used to genetically enhance different cancer-killing properties of human immune cells. Pickar-Oliver and Gersbach, 2019, Nature Reviews Molecular Cell Biology 20(8), 490-507.
Considering the potential application of the CRISPR-Cas9 system in the immunotherapy space, it is helpful to stay abreast of developments concerning the patenting of this technology. While there are a plethora of patents and patent applications relating to CRISPR,
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